Intramolecular guanidine epoxide ring opening reactions

Mark Dennis, Louise M. Hall, Patrick J. Murphy, Andrew J. Thornhill, Robert J. Nash, Ana L. Winters, Michael B. Hursthouse, Mark E. Light, Peter Horton

Research output: Contribution to journalArticlepeer-review

23 Citations (SciVal)

Abstract

The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.
Original languageEnglish
Pages (from-to)3075-3080
Number of pages6
JournalTetrahedron Letters
Volume44
Issue number15
Early online date21 Mar 2003
DOIs
Publication statusPublished - 07 Apr 2003

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