Intramolecular guanidine epoxide ring opening reactions

Mark Dennis; Louise M. Hall; Patrick J. Murphy; Andrew J. Thornhill; Robert J. Nash; Ana L. Winters; Michael B. Hursthouse; Mark E. Light; Peter Horton

doi:10.1016/S0040-4039(03)00519-7

Intramolecular guanidine epoxide ring opening reactions

Mark Dennis, Louise M. Hall, Patrick J. Murphy, Andrew J. Thornhill, Robert J. Nash, Ana L. Winters, Michael B. Hursthouse, Mark E. Light, Peter Horton

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.

Original language	English
Pages (from-to)	3075-3080
Number of pages	6
Journal	Tetrahedron Letters
Volume	44
Issue number	15
Early online date	21 Mar 2003
DOIs	https://doi.org/10.1016/S0040-4039(03)00519-7
Publication status	Published - 07 Apr 2003

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http://hdl.handle.net/2160/4147

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title = "Intramolecular guanidine epoxide ring opening reactions",

abstract = "The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.",

author = "Mark Dennis and Hall, {Louise M.} and Murphy, {Patrick J.} and Thornhill, {Andrew J.} and Nash, {Robert J.} and Winters, {Ana L.} and Hursthouse, {Michael B.} and Light, {Mark E.} and Peter Horton",

note = "Dennis, M., Hall, L. M., Murphy. P. J., Thornhill, A. J., Nash, R., Winters, A. L., Hursthouse, M. B., Light, M. E., Horton, P. (2003). Intramolecular guanidine epoxide ring opening reactions. Tetrahedron Letters, 44 (15), 3075-3080. Sponsorship: EPSRC",

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T1 - Intramolecular guanidine epoxide ring opening reactions

AU - Dennis, Mark

AU - Hall, Louise M.

AU - Murphy, Patrick J.

AU - Thornhill, Andrew J.

AU - Nash, Robert J.

AU - Winters, Ana L.

AU - Hursthouse, Michael B.

AU - Light, Mark E.

AU - Horton, Peter

N1 - Dennis, M., Hall, L. M., Murphy. P. J., Thornhill, A. J., Nash, R., Winters, A. L., Hursthouse, M. B., Light, M. E., Horton, P. (2003). Intramolecular guanidine epoxide ring opening reactions. Tetrahedron Letters, 44 (15), 3075-3080. Sponsorship: EPSRC

PY - 2003/4/7

Y1 - 2003/4/7

N2 - The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.

AB - The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.

U2 - 10.1016/S0040-4039(03)00519-7

DO - 10.1016/S0040-4039(03)00519-7

M3 - Article

SN - 0040-4039

VL - 44

SP - 3075

EP - 3080

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 15

ER -

Intramolecular guanidine epoxide ring opening reactions

Abstract

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