Intramolecular guanidine epoxide ring opening reactions

Mark Dennis; Louise M. Hall; Patrick J. Murphy; Andrew J. Thornhill; Robert J. Nash; Ana L. Winters; Michael B. Hursthouse; Mark E. Light; Peter Horton

doi:10.1016/S0040-4039(03)00519-7

Intramolecular guanidine epoxide ring opening reactions

Mark Dennis
, Louise M. Hall
, Patrick J. Murphy
, Andrew J. Thornhill
, Robert J. Nash
, Ana L. Winters
, Michael B. Hursthouse
, Mark E. Light
, Peter Horton

Institute of Biological, Environmental, and Rural Sciences

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.

Original language	English
Pages (from-to)	3075-3080
Number of pages	6
Journal	Tetrahedron Letters
Volume	44
Issue number	15
Early online date	21 Mar 2003
DOIs	https://doi.org/10.1016/S0040-4039(03)00519-7
Publication status	Published - 07 Apr 2003

Access to Document

10.1016/S0040-4039(03)00519-7

http://hdl.handle.net/2160/4147

Permanent link

Persistent link

Cite this

@article{00e7a38a72054156a042f9e7e1c74617,

title = "Intramolecular guanidine epoxide ring opening reactions",

abstract = "The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.",

author = "Mark Dennis and Hall, \{Louise M.\} and Murphy, \{Patrick J.\} and Thornhill, \{Andrew J.\} and Nash, \{Robert J.\} and Winters, \{Ana L.\} and Hursthouse, \{Michael B.\} and Light, \{Mark E.\} and Peter Horton",

note = "Dennis, M., Hall, L. M., Murphy. P. J., Thornhill, A. J., Nash, R., Winters, A. L., Hursthouse, M. B., Light, M. E., Horton, P. (2003). Intramolecular guanidine epoxide ring opening reactions. Tetrahedron Letters, 44 (15), 3075-3080. Sponsorship: EPSRC",

year = "2003",

month = apr,

day = "7",

doi = "10.1016/S0040-4039(03)00519-7",

language = "English",

volume = "44",

pages = "3075--3080",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "15",

}

TY - JOUR

T1 - Intramolecular guanidine epoxide ring opening reactions

AU - Dennis, Mark

AU - Hall, Louise M.

AU - Murphy, Patrick J.

AU - Thornhill, Andrew J.

AU - Nash, Robert J.

AU - Winters, Ana L.

AU - Hursthouse, Michael B.

AU - Light, Mark E.

AU - Horton, Peter

N1 - Dennis, M., Hall, L. M., Murphy. P. J., Thornhill, A. J., Nash, R., Winters, A. L., Hursthouse, M. B., Light, M. E., Horton, P. (2003). Intramolecular guanidine epoxide ring opening reactions. Tetrahedron Letters, 44 (15), 3075-3080. Sponsorship: EPSRC

PY - 2003/4/7

Y1 - 2003/4/7

N2 - The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.

AB - The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed. The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported, together with a preliminary investigation of the glycosidase inhibitory activity of these substances.

U2 - 10.1016/S0040-4039(03)00519-7

DO - 10.1016/S0040-4039(03)00519-7

M3 - Article

SN - 0040-4039

VL - 44

SP - 3075

EP - 3080

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 15

ER -

Intramolecular guanidine epoxide ring opening reactions

Abstract

Access to Document

Permanent link

Fingerprint

Cite this