Moving nitrogen to the centre of plant defence against pathogens

Luis Mur, Catherine Simpson, Aprajita Kumari, Alok Kumar Gupta, Kapuganti Jagadis Gupta

Research output: Contribution to journalArticlepeer-review

158 Citations (SciVal)
111 Downloads (Pure)

Abstract

Background
Plants require nitrogen (N) for growth, development and defence against abiotic and biotic stresses. The extensive use of artificial N fertilizers has played an important role in the Green Revolution. N assimilation can involve a reductase series (NO–3NO3– → NO–2NO2– → NH+4NH4+) followed by transamination to form amino acids. Given its widespread use, the agricultural impact of N nutrition on disease development has been extensively examined.

Scope
When a pathogen first comes into contact with a host, it is usually nutrient starved such that rapid assimilation of host nutrients is essential for successful pathogenesis. Equally, the host may reallocate its nutrients to defence responses or away from the site of attempted infection. Exogenous application of N fertilizer can, therefore, shift the balance in favour of the host or pathogen. In line with this, increasing N has been reported either to increase or to decrease plant resistance to pathogens, which reflects differences in the infection strategies of discrete pathogens. Beyond considering only N content, the use of NO–3NO3– or NH+4NH4+ fertilizers affects the outcome of plant–pathogen interactions. NO–3NO3– feeding augments hypersensitive response- (HR) mediated resistance, while ammonium nutrition can compromise defence. Metabolically, NO–3NO3– enhances production of polyamines such as spermine and spermidine, which are established defence signals, with NH+4NH4+ nutrition leading to increased γ-aminobutyric acid (GABA) levels which may be a nutrient source for the pathogen. Within the defensive N economy, the roles of nitric oxide must also be considered. This is mostly generated from NO–2NO2– by nitrate reductase and is elicited by both pathogen-associated microbial patterns and gene-for-gene-mediated defences. Nitric oxide (NO) production and associated defences are therefore NO–3NO3– dependent and are compromised by NH+4NH4+.

Conclusion
This review demonstrates how N content and form plays an essential role in defensive primary and secondary metabolism and NO-mediated events.
Original languageEnglish
Pages (from-to)703-709
Number of pages7
JournalAnnals of Botany
Early online date04 Sept 2016
DOIs
Publication statusPublished - 01 Mar 2017

Keywords

  • nitric oxide
  • nitrate
  • ammonium
  • Pseudomonas
  • nitrate reductase
  • polyamines
  • plant defence

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