Polyhydroxylated alkaloids - natural occurrence and therapeutic applications

Naoki Asano; George W. J. Fleet; Alison A. Watson; Russell J. Molyneux; Robert J. Nash

doi:10.1016/S0031-9422(00)00451-9

Polyhydroxylated alkaloids - natural occurrence and therapeutic applications

Naoki Asano, George W. J. Fleet, Alison A. Watson, Russell J. Molyneux, Robert J. Nash

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. These alkaloids can be potent and highly selective glycosidase inhibitors and are arousing great interest as tools to study cellular recognition and as potential therapeutic agents. However, only three of the natural products so far have been widely studied for therapeutic potential due largely to the limited commercial availability of the other compounds.

Original language	English
Pages (from-to)	265-295
Number of pages	31
Journal	Phytochemistry
DOIs	https://doi.org/10.1016/S0031-9422(00)00451-9
Publication status	Published - 2001

Access to Document

10.1016/S0031-9422(00)00451-9

http://hdl.handle.net/2160/3519

Permanent link

Persistent link

Cite this

@article{6c78990598224ff688bae68e1053c713,

title = "Polyhydroxylated alkaloids - natural occurrence and therapeutic applications",

abstract = "Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. These alkaloids can be potent and highly selective glycosidase inhibitors and are arousing great interest as tools to study cellular recognition and as potential therapeutic agents. However, only three of the natural products so far have been widely studied for therapeutic potential due largely to the limited commercial availability of the other compounds.",

author = "Naoki Asano and Fleet, {George W. J.} and Watson, {Alison A.} and Molyneux, {Russell J.} and Nash, {Robert J.}",

note = "Watson, A. A., Fleet, G. W. J., Asano, N., Molyneux, R. J., Nash, R. J. (2001). Polyhydroxylated alkaloids - natural occurrence and therapeutic applications. Phytochemistry, 56, 265-295",

year = "2001",

doi = "10.1016/S0031-9422(00)00451-9",

language = "English",

pages = "265--295",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier",

}

TY - JOUR

T1 - Polyhydroxylated alkaloids - natural occurrence and therapeutic applications

AU - Asano, Naoki

AU - Fleet, George W. J.

AU - Watson, Alison A.

AU - Molyneux, Russell J.

AU - Nash, Robert J.

N1 - Watson, A. A., Fleet, G. W. J., Asano, N., Molyneux, R. J., Nash, R. J. (2001). Polyhydroxylated alkaloids - natural occurrence and therapeutic applications. Phytochemistry, 56, 265-295

PY - 2001

Y1 - 2001

N2 - Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. These alkaloids can be potent and highly selective glycosidase inhibitors and are arousing great interest as tools to study cellular recognition and as potential therapeutic agents. However, only three of the natural products so far have been widely studied for therapeutic potential due largely to the limited commercial availability of the other compounds.

AB - Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. These alkaloids can be potent and highly selective glycosidase inhibitors and are arousing great interest as tools to study cellular recognition and as potential therapeutic agents. However, only three of the natural products so far have been widely studied for therapeutic potential due largely to the limited commercial availability of the other compounds.

U2 - 10.1016/S0031-9422(00)00451-9

DO - 10.1016/S0031-9422(00)00451-9

M3 - Article

SN - 0031-9422

SP - 265

EP - 295

JO - Phytochemistry

JF - Phytochemistry

ER -

Polyhydroxylated alkaloids - natural occurrence and therapeutic applications

Abstract

Access to Document

Permanent link

Fingerprint

Cite this