Rethinking Schistosomiasis Vaccine Development: Synthetic Vesicles

Moses Egesa, Karl Hoffmann, Cornelis H. Hokke, Maria Yazdanbakhsh, Stephen Cose

Research output: Contribution to journalArticlepeer-review

15 Citations (SciVal)
225 Downloads (Pure)

Abstract

There is currently no vaccine against schistosomiasis. With few Schistosoma vaccine candidates in clinical trials, unexplored antigens from the vulnerable schistosomulum should be considered as possible vaccine candidates. In addition, we suggest developing synthetic vesicles as a new delivery vehicle and adjuvant for immunoprophylactic schistosomula vaccine candidates.
Original languageEnglish
Article number1671
Pages (from-to)918-921
Number of pages4
JournalTrends in Parasitology
Volume33
Issue number12
Early online date14 Aug 2017
DOIs
Publication statusPublished - 01 Dec 2017

Keywords

  • Schistosoma
  • schistosomula
  • synthetic vesicles
  • vaccine candidates
  • delivery
  • adjuvant

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