RNAi: What is its position in agriculture?

Bruno Mezzetti*, Guy Smagghe, Salvatore Arpaia, Olivier Christiaens, Antje Dietz-Pfeilstetter, Huw Jones, Kaloyan Kostov, Silvia Sabbadini, Hilde Gunn Opsahl-Sorteberg, Vera Ventura, Clauvis Nji Tizi Taning, Jeremy Sweet

*Corresponding author for this work

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RNA interference (RNAi) is being developed and exploited to improve plants by modifying endogenous gene expression as well as to target pest and pathogen genes both within plants (i.e. host-induced gene silencing) and/or as topical applications (e.g. spray-induced gene silencing). RNAi is a natural mechanism which can be exploited to make a major contribution towards integrated pest management and sustainable agricultural strategies needed worldwide to secure current and future food production. RNAi plants are being assessed and regulated using existing regulatory frameworks for GMO. However, there is an urgent need to develop appropriate science-based risk assessment procedures for topical RNAi applications within existing plant protection products legislation.

Original languageEnglish
Pages (from-to)1125-1130
Number of pages6
JournalJournal of Pest Science
Issue number4
Early online date26 May 2020
Publication statusPublished - 01 Sept 2020


  • Agriculture
  • Biosafety
  • dsRNA
  • HIGS
  • Regulations
  • RNAi
  • SIGS
  • Rapid Communication


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  • Correction to: RNAi, what is its position in crop protection?

    Mezzetti, B., Smagghe, G., Arpaia, S., Christiaens, O., Dietz-Pfeilstetter, A., Jones, H., Kostov, K., Sabbadini, S., Opsahl-Sorteberg, H. G., Ventura, V., Taning, C. N. T. & Sweet, J., 01 Sept 2021, In: Journal of Pest Science. 94, 4, 1 p., 1555.

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    Open Access
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