Sequence heterogeneity of an mpb70 gene analogue in Mycobacterium kansasii

Alison J Woolford; R.glyn Hewinson; Martin Woodward; Jeremy W Dale

doi:10.1111/j.1574-6968.1997.tb10264.x

Sequence heterogeneity of an mpb70 gene analogue in Mycobacterium kansasii

Alison J Woolford, R.glyn Hewinson, Martin Woodward, Jeremy W Dale

Bovine TB, diseases and control

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

The protein antigen MPB70 is a major component of culture supernatants of Mycobacterium bovis and is an active ingredient of bovine PPD used for skin-testing cattle for tuberculosis. We have shown that Mycobacterium kansasii possesses a similar gene that cross-reacts in a PCR test for M. bovis. Single strand conformational polymorphism analysis, and the DNA sequence of the PCR product, shows differences between M. kansasii strains, supporting the suggestion that M. kansasii is not a homogeneous species.

Original language	English
Pages (from-to)	43-48
Number of pages	6
Journal	FEMS Microbiology Letters
Volume	148
Issue number	1
DOIs	https://doi.org/10.1111/j.1574-6968.1997.tb10264.x
Publication status	Published - 01 Mar 1997

Keywords

bovine tuberculosis
MPB70 antigen
Mycobacterium kansasii

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1574-6968.1997.tb10264.x

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AU - Woodward, Martin

AU - Dale, Jeremy W

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Sequence heterogeneity of an mpb70 gene analogue in Mycobacterium kansasii

Abstract

Keywords

UN SDGs

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