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Sequence heterogeneity of an mpb70 gene analogue in Mycobacterium kansasii

  • University of Surrey
  • Animal and Plant Health Agency

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The protein antigen MPB70 is a major component of culture supernatants of Mycobacterium bovis and is an active ingredient of bovine PPD used for skin-testing cattle for tuberculosis. We have shown that Mycobacterium kansasii possesses a similar gene that cross-reacts in a PCR test for M. bovis. Single strand conformational polymorphism analysis, and the DNA sequence of the PCR product, shows differences between M. kansasii strains, supporting the suggestion that M. kansasii is not a homogeneous species.
Original languageEnglish
Pages (from-to)43-48
Number of pages6
JournalFEMS Microbiology Letters
Volume148
Issue number1
DOIs
Publication statusPublished - 01 Mar 1997

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • bovine tuberculosis
  • MPB70 antigen
  • Mycobacterium kansasii

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