T-Cell Responses in Mice Immunised with Live aroA Salmonella Vaccines

Bernardo Villarreal, Pietro Mastroeni, Raquel Demarco De Hormaeche, Carlos E. Hormaeche

Research output: Chapter in Book/Report/Conference proceedingChapter


The search for of improved salmonella vaccines has seen the development of live attenuated salmonellae with lesions in genes of the aromatic pathway (Aro vaccines). These can be given orally, cause few side reactions and confer excellent protection in animals and are being tested in humans. They can also be used to deliver recombinant antigens from other pathogens as combined vaccines.
Original languageEnglish
Title of host publicationBiology of Salmonella
EditorsFelipe Cabello, Carlos Hormaeche, Pasquale Mastroeni, Letterio Bonina
PublisherSpringer Nature
ISBN (Electronic)9781461528548
ISBN (Print)9781461362364, 9780306444920
Publication statusPublished - 12 Dec 1992


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