The immune system in pieces: Computational lessons from degeneracy in the immune system

M. Mendao; J. Timmis; P. S. Andrews

doi:10.1109/FOCI.2007.371502

The immune system in pieces: Computational lessons from degeneracy in the immune system

M. Mendao^*, J. Timmis, P. S. Andrews

^*Corresponding author for this work

Department of Computer Science

University of York

Research output: Chapter in Book/Report/Conference proceeding › Conference Proceeding (Non-Journal item)

17 Citations (Scopus)

Abstract

The concept of degeneracy in biology, including the immune system, is well accepted and has been demonstrated to be present at many different levels. We explore this concept from a computational point of view and demonstrate how we can use computational models of degeneracy to aid the development of more biologically plausible Artificial Immune Systems (AIS). The outcome of these models has lead us to perform an analysis of the receptor dynamics in the model and we discuss the computational implications of a "degenerate" repertoire. Through the use of the Unified Modelling language (UML) we have abstracted a high level immune inspire algorithm that will be used as part of a larger project to develop an immune inspired bioinformatics system.

Original language	English
Title of host publication	Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007
Pages	394-400
Number of pages	7
DOIs	https://doi.org/10.1109/FOCI.2007.371502
Publication status	Published - 2007
Event	2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007 - Honolulu, HI, United States of America Duration: 01 Apr 2007 → 05 Apr 2007

Publication series

Name	Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007

Conference

Conference	2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007
Country/Territory	United States of America
City	Honolulu, HI
Period	01 Apr 2007 → 05 Apr 2007

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10.1109/FOCI.2007.371502

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Mendao, M., Timmis, J., & Andrews, P. S. (2007). The immune system in pieces: Computational lessons from degeneracy in the immune system. In Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007 (pp. 394-400). Article 4233936 (Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007). https://doi.org/10.1109/FOCI.2007.371502

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Mendao, M, Timmis, J & Andrews, PS 2007, The immune system in pieces: Computational lessons from degeneracy in the immune system. in Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007., 4233936, Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007, pp. 394-400, 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007, Honolulu, HI, United States of America, 01 Apr 2007. https://doi.org/10.1109/FOCI.2007.371502

The immune system in pieces: Computational lessons from degeneracy in the immune system. / Mendao, M.; Timmis, J.; Andrews, P. S.
Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007. 2007. p. 394-400 4233936 (Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007).

Research output: Chapter in Book/Report/Conference proceeding › Conference Proceeding (Non-Journal item)

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Mendao M, Timmis J, Andrews PS. The immune system in pieces: Computational lessons from degeneracy in the immune system. In Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007. 2007. p. 394-400. 4233936. (Proceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007). doi: 10.1109/FOCI.2007.371502

The immune system in pieces: Computational lessons from degeneracy in the immune system

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