The immune system in pieces: Computational lessons from degeneracy in the immune system

M. Mendao*, J. Timmis, P. S. Andrews

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference Proceeding (Non-Journal item)

17 Citations (SciVal)

Abstract

The concept of degeneracy in biology, including the immune system, is well accepted and has been demonstrated to be present at many different levels. We explore this concept from a computational point of view and demonstrate how we can use computational models of degeneracy to aid the development of more biologically plausible Artificial Immune Systems (AIS). The outcome of these models has lead us to perform an analysis of the receptor dynamics in the model and we discuss the computational implications of a "degenerate" repertoire. Through the use of the Unified Modelling language (UML) we have abstracted a high level immune inspire algorithm that will be used as part of a larger project to develop an immune inspired bioinformatics system.

Original languageEnglish
Title of host publicationProceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007
Pages394-400
Number of pages7
DOIs
Publication statusPublished - 2007
Event2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007 - Honolulu, HI, United States of America
Duration: 01 Apr 200705 Apr 2007

Publication series

NameProceedings of the 2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007

Conference

Conference2007 IEEE Symposium on Foundations of Computational Intelligence, FOCI 2007
Country/TerritoryUnited States of America
CityHonolulu, HI
Period01 Apr 200705 Apr 2007

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