The rise in computational systems biology approaches for understanding NF-κB signaling dynamics

Richard A. Williams*, Jon Timmis, Eva E. Qwarnstrom

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (SciVal)

Abstract

A study by Cheng et al. in this issue of Science Signaling highlights the distinct single-cell signaling characteristics conferred by pathways mediated by the adaptor proteins MyD88 and TRIF in the TLR4-dependent activation of the transcription factor nuclear factor κB (NF-κB).

Original languageEnglish
Article numberfs13
JournalScience Signaling
Volume8
Issue number385
DOIs
Publication statusPublished - 14 Jul 2015
Externally publishedYes

Keywords

  • Adaptor Proteins, Vesicular Transport/metabolism
  • Animals
  • Myeloid Differentiation Factor 88/metabolism
  • Signal Transduction/physiology
  • Toll-Like Receptor 4/metabolism

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