Tuberculosis outbreak in a dromedary racing herd and rapid serological detection of infected camels

U. Wernery; J. Kinne; K. L. Jahans; H. M. Vordermeier; J. Esfandiari; R. Greenwald; B. Johnson; A. Ul-Haq; K. P. Lyashchenko

doi:10.1016/j.vetmic.2007.01.012

Tuberculosis outbreak in a dromedary racing herd and rapid serological detection of infected camels

U. Wernery, J. Kinne, K. L. Jahans, H. M. Vordermeier, J. Esfandiari, R. Greenwald, B. Johnson, A. Ul-Haq, K. P. Lyashchenko^*

^*Corresponding author for this work

Bovine TB, diseases and control

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

A recent outbreak of tuberculosis (TB) in a dromedary racing herd of 58 animals involved 3 infected animals. Disease was confirmed at necropsy by finding gross lesions from which Mycobacterium bovis (antelope type) was isolated. Sera collected from the camels in this herd were used to evaluate two new serological methods, Multiantigen Print Immunoassay (MAPIA) and rapid test (RT) developed using the lateral-flow technology, in comparison with the intradermal tuberculin tests. Antibodies were found in all three infected dromedaries by both RT and MAPIA, but not in the remaining 55 animals in the herd. With the limited number of animals tested in this study, the serological assays showed the potential for convenient, rapid, and accurate diagnosis of TB in live camels.

Original language	English
Pages (from-to)	108-115
Number of pages	8
Journal	Veterinary Microbiology
Volume	122
Issue number	1-2
Early online date	20 Jan 2007
DOIs	https://doi.org/10.1016/j.vetmic.2007.01.012
Publication status	Published - 16 May 2007

Keywords

Camel
Mycobacterium bovis
Serology
Skin test
Tuberculosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.vetmic.2007.01.012

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title = "Tuberculosis outbreak in a dromedary racing herd and rapid serological detection of infected camels",

abstract = "A recent outbreak of tuberculosis (TB) in a dromedary racing herd of 58 animals involved 3 infected animals. Disease was confirmed at necropsy by finding gross lesions from which Mycobacterium bovis (antelope type) was isolated. Sera collected from the camels in this herd were used to evaluate two new serological methods, Multiantigen Print Immunoassay (MAPIA) and rapid test (RT) developed using the lateral-flow technology, in comparison with the intradermal tuberculin tests. Antibodies were found in all three infected dromedaries by both RT and MAPIA, but not in the remaining 55 animals in the herd. With the limited number of animals tested in this study, the serological assays showed the potential for convenient, rapid, and accurate diagnosis of TB in live camels.",

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AU - Wernery, U.

AU - Kinne, J.

AU - Jahans, K. L.

AU - Vordermeier, H. M.

AU - Esfandiari, J.

AU - Greenwald, R.

AU - Johnson, B.

AU - Ul-Haq, A.

AU - Lyashchenko, K. P.

PY - 2007/5/16

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N2 - A recent outbreak of tuberculosis (TB) in a dromedary racing herd of 58 animals involved 3 infected animals. Disease was confirmed at necropsy by finding gross lesions from which Mycobacterium bovis (antelope type) was isolated. Sera collected from the camels in this herd were used to evaluate two new serological methods, Multiantigen Print Immunoassay (MAPIA) and rapid test (RT) developed using the lateral-flow technology, in comparison with the intradermal tuberculin tests. Antibodies were found in all three infected dromedaries by both RT and MAPIA, but not in the remaining 55 animals in the herd. With the limited number of animals tested in this study, the serological assays showed the potential for convenient, rapid, and accurate diagnosis of TB in live camels.

AB - A recent outbreak of tuberculosis (TB) in a dromedary racing herd of 58 animals involved 3 infected animals. Disease was confirmed at necropsy by finding gross lesions from which Mycobacterium bovis (antelope type) was isolated. Sera collected from the camels in this herd were used to evaluate two new serological methods, Multiantigen Print Immunoassay (MAPIA) and rapid test (RT) developed using the lateral-flow technology, in comparison with the intradermal tuberculin tests. Antibodies were found in all three infected dromedaries by both RT and MAPIA, but not in the remaining 55 animals in the herd. With the limited number of animals tested in this study, the serological assays showed the potential for convenient, rapid, and accurate diagnosis of TB in live camels.

KW - Camel

KW - Mycobacterium bovis

KW - Serology

KW - Skin test

KW - Tuberculosis

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JO - Veterinary Microbiology

JF - Veterinary Microbiology

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ER -

Tuberculosis outbreak in a dromedary racing herd and rapid serological detection of infected camels

Abstract

Keywords

UN SDGs

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