Using ontologies to describe mouse phenotypes

Georgios V Gkoutos; Eain C. J. Green; Ann-Marie Mallon; John M Hancock; Duncan Davidson

Using ontologies to describe mouse phenotypes

Georgios V Gkoutos
, Eain C. J. Green
, Ann-Marie Mallon
, John M Hancock
, Duncan Davidson

Department of Computer Science

Research output: Contribution to journal › Article › peer-review

Abstract

The mouse is an important model of human genetic disease. Describing phenotypes of mutant mice in a standard, structured manner that will facilitate data mining is a major challenge for bioinformatics. Here we describe a novel, compositional approach to this problem which combines core ontologies from a variety of sources. This produces a framework with greater flexibility, power and economy than previous approaches. We discuss some of the issues this approach raises.

Original language	English
Pages (from-to)	R8
Journal	Genome Biology
Volume	6
Issue number	1
Publication status	Published - 2004

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Permanent link

Persistent link

Cite this

@article{ae21cf148a5c4b68b30f45ffff075b62,

title = "Using ontologies to describe mouse phenotypes",

abstract = "The mouse is an important model of human genetic disease. Describing phenotypes of mutant mice in a standard, structured manner that will facilitate data mining is a major challenge for bioinformatics. Here we describe a novel, compositional approach to this problem which combines core ontologies from a variety of sources. This produces a framework with greater flexibility, power and economy than previous approaches. We discuss some of the issues this approach raises. ",

author = "Gkoutos, \{Georgios V\} and Green, \{Eain C. J.\} and Ann-Marie Mallon and Hancock, \{John M\} and Duncan Davidson",

year = "2004",

language = "English",

volume = "6",

pages = "R8",

journal = "Genome Biology",

issn = "1474-760X",

publisher = "Springer Nature",

number = "1",

}

TY - JOUR

T1 - Using ontologies to describe mouse phenotypes

AU - Gkoutos, Georgios V

AU - Green, Eain C. J.

AU - Mallon, Ann-Marie

AU - Hancock, John M

AU - Davidson, Duncan

PY - 2004

Y1 - 2004

N2 - The mouse is an important model of human genetic disease. Describing phenotypes of mutant mice in a standard, structured manner that will facilitate data mining is a major challenge for bioinformatics. Here we describe a novel, compositional approach to this problem which combines core ontologies from a variety of sources. This produces a framework with greater flexibility, power and economy than previous approaches. We discuss some of the issues this approach raises.

AB - The mouse is an important model of human genetic disease. Describing phenotypes of mutant mice in a standard, structured manner that will facilitate data mining is a major challenge for bioinformatics. Here we describe a novel, compositional approach to this problem which combines core ontologies from a variety of sources. This produces a framework with greater flexibility, power and economy than previous approaches. We discuss some of the issues this approach raises.

UR - http://hdl.handle.net/2160/12066

M3 - Article

SN - 1474-760X

VL - 6

SP - R8

JO - Genome Biology

JF - Genome Biology

IS - 1

ER -

Using ontologies to describe mouse phenotypes

Abstract

UN SDGs

Permanent link

Other files and links

Fingerprint

Cite this