Vaccination of domestic animals against tuberculosis: Review of progress and contributions to the field of the TBSTEP project

H. Martin Vordermeier*, Bernat Pérez de Val, Bryce M. Buddle, Bernardo Villarreal-Ramos, Gareth J. Jones, R. Glyn Hewinson, Mariano Domingo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (SciVal)

Abstract

Tuberculosis either caused by Mycobacterium bovis or M. caprae is a significant burden to agricultural industries worldwide. Vaccination of domestic ruminant species such as cattle and goats constitutes a potential tool to support disease control. This review will discuss recent progress made to develop tuberculosis vaccines against domestic ruminants as well as approaches to differentiate vaccinated and infected animals (DIVA) and biomarker discovery studies.

Original languageEnglish
Pages (from-to)S53-S60
JournalResearch in Veterinary Science
Volume97 Suppl
Issue numberS
Early online date06 May 2014
DOIs
Publication statusPublished - 01 Oct 2014

Keywords

  • Biomarkers
  • Cattle
  • DIVA
  • Goats
  • Tuberculosis
  • Vaccination
  • Diagnosis, Differential
  • Mycobacterium bovis/immunology
  • Mycobacterium tuberculosis/immunology
  • Europe
  • Tuberculosis, Bovine/diagnosis
  • Animals, Domestic
  • Tuberculosis Vaccines/immunology
  • Vaccination/trends
  • Animals
  • Tuberculosis/immunology
  • BCG Vaccine/immunology
  • Goat Diseases/diagnosis
  • Ruminants

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