Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

Mark A. Chambers, Tim Crawshaw, Sue Waterhouse, Richard Delahay, R. Glyn Hewinson, Konstantin P. Lyashchenko

Research output: Contribution to journalArticlepeer-review

63 Citations (Scopus)

Abstract

A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.

Original languageEnglish
Pages (from-to)1498-1500
Number of pages3
JournalJournal of Clinical Microbiology
Volume46
Issue number4
Early online date13 Feb 2008
DOIs
Publication statusPublished - 01 Apr 2008

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