Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

Mark A. Chambers; Tim Crawshaw; Sue Waterhouse; Richard Delahay; R. Glyn Hewinson; Konstantin P. Lyashchenko

doi:10.1128/JCM.02117-07

Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

Mark A. Chambers
, Tim Crawshaw
, Sue Waterhouse
, Richard Delahay
, R. Glyn Hewinson
, Konstantin P. Lyashchenko

Bovine TB, diseases and control

Research output: Contribution to journal › Article › peer-review

64 Citations (Scopus)

Abstract

A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.

Original language	English
Pages (from-to)	1498-1500
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	46
Issue number	4
Early online date	13 Feb 2008
DOIs	https://doi.org/10.1128/JCM.02117-07
Publication status	Published - 01 Apr 2008

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abstract = "A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49\% sensitive and 93\% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78\%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.",

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AU - Delahay, Richard

AU - Hewinson, R. Glyn

AU - Lyashchenko, Konstantin P.

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Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

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