Visualization of multiple alignments, phylogenies and gene family evolution

James B Procter; Julie Thompson; Ivica Letunic; Christopher James Creevey; Fabrice Jossinet; Geoffrey J Barton

doi:10.1038/nmeth.1434

Visualization of multiple alignments, phylogenies and gene family evolution

James B Procter, Julie Thompson, Ivica Letunic, Christopher James Creevey, Fabrice Jossinet, Geoffrey J Barton

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

Software for visualizing sequence alignments and trees are essential tools for life scientists. In this review, we describe the major features and capabilities of a selection of stand-alone and web-based applications useful when investigating the function and evolution of a gene family. These range from simple viewers, to systems that provide sophisticated editing and analysis functions. We conclude with a discussion of the challenges that these tools now face due to the flood of next generation sequence data and the increasingly complex network of bioinformatics information sources.

Original language	English
Pages (from-to)	S16-25
Journal	Nature Methods
Volume	7
Issue number	3 Suppl
DOIs	https://doi.org/10.1038/nmeth.1434
Publication status	Published - 2010

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AU - Letunic, Ivica

AU - Creevey, Christopher James

AU - Jossinet, Fabrice

AU - Barton, Geoffrey J

PY - 2010

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AB - Software for visualizing sequence alignments and trees are essential tools for life scientists. In this review, we describe the major features and capabilities of a selection of stand-alone and web-based applications useful when investigating the function and evolution of a gene family. These range from simple viewers, to systems that provide sophisticated editing and analysis functions. We conclude with a discussion of the challenges that these tools now face due to the flood of next generation sequence data and the increasingly complex network of bioinformatics information sources.

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DO - 10.1038/nmeth.1434

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ER -

Visualization of multiple alignments, phylogenies and gene family evolution

Abstract

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