Development of a Dictyostelium discoideum (slime mould) based rapid drug screening system to identify potential anti-protozoan drugs

  • Shane Collett

Student thesis: Master's ThesisMaster of Philosophy


Dictyostelium discoideum is a free living social amoeba, which are able to change from a single celled organism to multicellular organism when in starvation condition. In this study, D. dicsoideum is being utilised as a model organism to screen over 400 compounds for activity against pathogenic protozoans. The technique evaluated using an agar based assay. Furthermore, three compounds were also identified as promising for further investigation for their anti-protozoan activity properties
Date of Award2022
Original languageEnglish
Awarding Institution
  • Aberystwyth University
SupervisorJustin Pachebat (Supervisor) & Joanne Hamilton (Supervisor)

Cite this